{
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  "Package": "MGDrivE",
  "Type": "Package",
  "Title": "Mosquito Gene Drive Explorer",
  "Version": "1.6.2",
  "Authors@R": "c(\nperson(\"Héctor Manuel\", \"Sánchez Castellanos\", email = \"sanchez.hmsc@berkeley.edu\", role = c(\"aut\",\"cre\")),\nperson(\"Jared\", \"Bennett\", email = \"jared_bennett@berkeley.edu \", role = \"aut\"),\nperson(\"Sean\", \"Wu\", email = \"slwu89@berkeley.edu\", role = \"aut\"),\nperson(\"John M.\", \"Marshall\", email = \"john.marshall@berkeley.edu\", role = \"aut\")\n)",
  "Maintainer": "Héctor Manuel Sánchez Castellanos\n<sanchez.hmsc@berkeley.edu>",
  "URL": "https://marshalllab.github.io/MGDrivE/,\nhttps://www.marshalllab.com/,\nhttps://marshalllab.github.io/MGDrivE/docs_v1",
  "BugReports": "https://github.com/MarshallLab/MGDrivE/issues",
  "Description": "Provides a model designed to be a reliable testbed where\nvarious gene drive interventions for mosquito-borne diseases\ncontrol. It is being developed to accommodate the use of\nvarious mosquito-specific gene drive systems within a\npopulation dynamics framework that allows migration of\nindividuals between patches in landscape. Previous work\ndeveloping the population dynamics can be found in Deredec et\nal. (2001) <doi:10.1073/pnas.1110717108> and Hancock & Godfray\n(2007) <doi:10.1186/1475-2875-6-98>, and extensions to\naccommodate CRISPR homing dynamics in Marshall et al. (2017)\n<doi:10.1038/s41598-017-02744-7>.",
  "License": "GPL-3",
  "Encoding": "UTF-8",
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  "Repository": "https://marshalllab.r-universe.dev",
  "Date/Publication": "2025-09-14 02:14:25 UTC",
  "RemoteUrl": "https://github.com/marshalllab/mgdrive",
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  "Packaged": {
    "Date": "2026-05-12 06:02:18 UTC",
    "User": "root"
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  "Author": "Héctor Manuel Sánchez Castellanos [aut, cre],\nJared Bennett [aut],\nSean Wu [aut],\nJohn M. Marshall [aut]",
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  "_published": "2026-05-22T11:03:21.552Z",
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    "name": "Marshall Lab",
    "description": "Our research is focused on: 1) genetics-based strategies to control mosquito-borne diseases, and 2) mathematical models to support vector-borne disease control."
  },
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  "_devurl": "https://github.com/marshalllab/mgdrive",
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  "_topics": [
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    "extra/citation.json",
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      "date": "2020-10-05"
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      "date": "2025-09-05"
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  "_exports": [
    "aggregateFemales",
    "aggregateOutput",
    "basicBatchMigration",
    "calcCos",
    "calcExpKernel",
    "calcGammaKernel",
    "calcHaversine",
    "calcHurdleExpKernel",
    "calcLognormalKernel",
    "calcOmega",
    "calcQuantiles",
    "calcVinEll",
    "calcVinSph",
    "calcZeroInflation",
    "cube2csv",
    "cubeAlleleSail",
    "cubeASmidler",
    "cubeCLEAVRMF",
    "cubeCLEAVRX",
    "cubeClvR",
    "cubeClvR2",
    "cubeConfinableHoming",
    "cubeConfinableHomingJOHN",
    "cubeConfinableHomingX",
    "cubeECHACR",
    "cubeECHACRX",
    "cubeHoming1RA",
    "cubeHomingDrive",
    "cubeHomingDriveSM",
    "cubeImmunizingReversalMF",
    "cubeImmunizingReversalX",
    "cubeKillerRescue",
    "cubeMEDEA",
    "cubeMendelian",
    "cubeOneLocusTA",
    "cubeReciprocalTranslocations",
    "cubeRIDL",
    "cubeSplitDrive",
    "cubeSplitDriveX",
    "cubeSplitDriveY",
    "cubeTGD",
    "cubeTGDX",
    "cubeTwoLocusTA",
    "cubeWolbachia",
    "cubeXHomingDeposition",
    "cubeXShredderMF",
    "cubeXShredderY",
    "eraseDirectory",
    "generateReleaseVector",
    "Network",
    "parameterizeMGDrivE",
    "plotMGDrivEMult",
    "plotMGDrivESingle",
    "retrieveOutput",
    "setupMGDrivE",
    "splitOutput"
  ],
  "_datasets": [
    {
      "name": "kernels",
      "title": "Kernels Parameters",
      "object": "kernels",
      "class": [
        "list"
      ],
      "fields": [],
      "table": true,
      "tojson": true
    },
    {
      "name": "moveMatAll2",
      "title": "Movement Matrix: All 2",
      "object": "moveMatAll2",
      "class": [
        "matrix",
        "array"
      ],
      "fields": {},
      "rows": 3,
      "table": true,
      "tojson": true
    },
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      "title": "Movement Matrix: Cascade 3",
      "object": "moveMatCascade3",
      "class": [
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        "array"
      ],
      "fields": {},
      "rows": 3,
      "table": true,
      "tojson": true
    },
    {
      "name": "moveMatDiag",
      "title": "Movement Matrix: Diagonal",
      "object": "moveMatDiag",
      "class": [
        "matrix",
        "array"
      ],
      "fields": {},
      "rows": 3,
      "table": true,
      "tojson": true
    },
    {
      "name": "moveMatDiagOneCity",
      "title": "Movement Matrix: Diagonal One City",
      "object": "moveMatDiagOneCity",
      "class": [
        "matrix",
        "array"
      ],
      "fields": {},
      "rows": 1,
      "table": true,
      "tojson": true
    },
    {
      "name": "moveMatDie",
      "title": "Movement Matrix: Die",
      "object": "moveMatDie",
      "class": [
        "matrix",
        "array"
      ],
      "fields": {},
      "rows": 3,
      "table": true,
      "tojson": true
    },
    {
      "name": "moveMatIndependent3",
      "title": "Movement Matrix: Independent 3",
      "object": "moveMatIndependent3",
      "class": [
        "matrix",
        "array"
      ],
      "fields": {},
      "rows": 3,
      "table": true,
      "tojson": true
    },
    {
      "name": "moveMatMixedSpil",
      "title": "Movement Matrix: Mixed Spill",
      "object": "moveMatMixedSpil",
      "class": [
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        "array"
      ],
      "fields": {},
      "rows": 3,
      "table": true,
      "tojson": true
    },
    {
      "name": "moveMatTaleOfTwoCities",
      "title": "Movement Matrix: Tale of Two Cities",
      "object": "moveMatTaleOfTwoCities",
      "class": [
        "matrix",
        "array"
      ],
      "fields": {},
      "rows": 2,
      "table": true,
      "tojson": true
    },
    {
      "name": "moveMatTriDiagonal",
      "title": "Movement Matrix: Tri-diagonal",
      "object": "moveMatTriDiagonal",
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        "array"
      ],
      "fields": [
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        "2",
        "3",
        "4",
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        "12"
      ],
      "rows": 12,
      "table": true,
      "tojson": true
    },
    {
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      "title": "Movement Matrix: Triple",
      "object": "moveMatTriple",
      "class": [
        "matrix",
        "array"
      ],
      "fields": {},
      "rows": 3,
      "table": true,
      "tojson": true
    }
  ],
  "_help": [
    {
      "page": "aggregateFemales",
      "title": "Aggregate Female Output by Genotype",
      "topics": [
        "aggregateFemales"
      ]
    },
    {
      "page": "aggregateOutput",
      "title": "Aggregate Output Over Landscape",
      "topics": [
        "aggregateOutput"
      ]
    },
    {
      "page": "basicBatchMigration",
      "title": "Make List of Batch Migration Parameters",
      "topics": [
        "basicBatchMigration"
      ]
    },
    {
      "page": "calcCos",
      "title": "Calculate Geodesic Distance - Cosine Method",
      "topics": [
        "calcCos"
      ]
    },
    {
      "page": "calcExpKernel",
      "title": "Calculate Exponential Stochastic Matrix",
      "topics": [
        "calcExpKernel"
      ]
    },
    {
      "page": "calcGammaKernel",
      "title": "Calculate Gamma Stochastic Matrix",
      "topics": [
        "calcGammaKernel"
      ]
    },
    {
      "page": "calcHaversine",
      "title": "Calculate Geodesic Distance - Haversine Method",
      "topics": [
        "calcHaversine"
      ]
    },
    {
      "page": "calcHurdleExpKernel",
      "title": "Calculate Zero-inflated Exponential Stochastic Matrix",
      "topics": [
        "calcHurdleExpKernel"
      ]
    },
    {
      "page": "calcLognormalKernel",
      "title": "Calculate Lognormal Stochastic Matrix",
      "topics": [
        "calcLognormalKernel"
      ]
    },
    {
      "page": "calcOmega",
      "title": "Solve for Omega (additional genotype-specific mortality)",
      "topics": [
        "calcOmega"
      ]
    },
    {
      "page": "calcQuantiles",
      "title": "Summary Statistics for Stochastic MGDrivE",
      "topics": [
        "calcQuantiles"
      ]
    },
    {
      "page": "calcVinEll",
      "title": "Calculate Geodesic Distance - Vincenty Ellipsoid Method",
      "topics": [
        "calcVinEll"
      ]
    },
    {
      "page": "calcVinSph",
      "title": "Calculate Geodesic Distance - Vincenty Sphere Method",
      "topics": [
        "calcVinSph"
      ]
    },
    {
      "page": "calcZeroInflation",
      "title": "Calculates the zero-inflation part of a hurdle exponential kernel.",
      "topics": [
        "calcZeroInflation"
      ]
    },
    {
      "page": "cube2csv",
      "title": "Export a Cube to .csv",
      "topics": [
        "cube2csv"
      ]
    },
    {
      "page": "cubeAlleleSail",
      "title": "Inheritance Cube: 3-Piece Allele Sail",
      "topics": [
        "cubeAlleleSail"
      ]
    },
    {
      "page": "cubeASmidler",
      "title": "Inheritance Cube: Split-Drive for Andrea Smidler",
      "topics": [
        "cubeASmidler"
      ]
    },
    {
      "page": "cubeCLEAVRMF",
      "title": "Inheritance Cube: CLEAVR - Cleave and Rescue",
      "topics": [
        "cubeCLEAVRMF"
      ]
    },
    {
      "page": "cubeCLEAVRX",
      "title": "Inheritance Cube: CLEAVR - Cleave and Rescue",
      "topics": [
        "cubeCLEAVRX"
      ]
    },
    {
      "page": "cubeClvR",
      "title": "Inheritance Cube: ClvR (Cleave and Rescue)",
      "topics": [
        "cubeClvR"
      ]
    },
    {
      "page": "cubeClvR2",
      "title": "Inheritance Cube: 2-Locus ClvR (Cleave and Rescue)",
      "topics": [
        "cubeClvR2"
      ]
    },
    {
      "page": "cubeConfinableHoming",
      "title": "Inheritance Cube: Confinable Homing",
      "topics": [
        "cubeConfinableHoming"
      ]
    },
    {
      "page": "cubeConfinableHomingJOHN",
      "title": "Inheritance Cube: Confinable Homing Drive, John",
      "topics": [
        "cubeConfinableHomingJOHN"
      ]
    },
    {
      "page": "cubeConfinableHomingX",
      "title": "Inheritance Cube: Confinable Homing, X-Linked",
      "topics": [
        "cubeConfinableHomingX"
      ]
    },
    {
      "page": "cubeECHACR",
      "title": "Inheritance Cube: ECHACR",
      "topics": [
        "cubeECHACR"
      ]
    },
    {
      "page": "cubeECHACRX",
      "title": "Inheritance Cube: ECHACRX",
      "topics": [
        "cubeECHACRX"
      ]
    },
    {
      "page": "cubeHoming1RA",
      "title": "Inheritance Cube: Homing Drive with 1 Resistance Allele",
      "topics": [
        "cubeHoming1RA"
      ]
    },
    {
      "page": "cubeHomingDrive",
      "title": "Inheritance Cube: CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) with 2 Resistance Alleles and maternal deposition",
      "topics": [
        "cubeHomingDrive"
      ]
    },
    {
      "page": "cubeHomingDriveSM",
      "title": "Inheritance Cube: CRISPR-SM (Clustered Regularly Interspaced Short Palindromic Repeats) with Small-Molecule Induction and 1 Resistance Allele and Maternal Deposition",
      "topics": [
        "cubeHomingDriveSM"
      ]
    },
    {
      "page": "cubeImmunizingReversalMF",
      "title": "Inheritance Cube: Immunizing Reversal/Basic Reversal",
      "topics": [
        "cubeImmunizingReversalMF"
      ]
    },
    {
      "page": "cubeImmunizingReversalX",
      "title": "Inheritance Cube: Immunizing Reversal",
      "topics": [
        "cubeImmunizingReversalX"
      ]
    },
    {
      "page": "cubeKillerRescue",
      "title": "Inheritance Cube: Killer-Rescue System",
      "topics": [
        "cubeKillerRescue"
      ]
    },
    {
      "page": "cubeMEDEA",
      "title": "Inheritance Cube: MEDEA (Maternal Effect Dominant Embryonic Arrest)",
      "topics": [
        "cubeMEDEA"
      ]
    },
    {
      "page": "cubeMendelian",
      "title": "Inheritance Cube: Mendelian",
      "topics": [
        "cubeMendelian"
      ]
    },
    {
      "page": "cubeOneLocusTA",
      "title": "Inheritance Cube: 1 Locus Maternal-Toxin/Zygotic-Antidote System",
      "topics": [
        "cubeOneLocusTA"
      ]
    },
    {
      "page": "cubeReciprocalTranslocations",
      "title": "Inheritance Cube: Reciprocal Translocation",
      "topics": [
        "cubeReciprocalTranslocations"
      ]
    },
    {
      "page": "cubeRIDL",
      "title": "Inheritance Cube: RIDL (Release of Insects with Dominant Lethality)",
      "topics": [
        "cubeRIDL"
      ]
    },
    {
      "page": "cubeSplitDrive",
      "title": "Inheritance Cube: Split CRISPR Drive with 2 Resistance Alleles and male/female specific homing",
      "topics": [
        "cubeSplitDrive"
      ]
    },
    {
      "page": "cubeSplitDriveX",
      "title": "Inheritance Cube: X-linked Split CRISPR Drive with 2 Resistance Alleles and male/female specific homing",
      "topics": [
        "cubeSplitDriveX"
      ]
    },
    {
      "page": "cubeSplitDriveY",
      "title": "Inheritance Cube: Y-linked Split CRISPR Drive with 2 Resistance Alleles",
      "topics": [
        "cubeSplitDriveY"
      ]
    },
    {
      "page": "cubeTGD",
      "title": "Inheritance Cube: tGD",
      "topics": [
        "cubeTGD"
      ]
    },
    {
      "page": "cubeTGDX",
      "title": "Inheritance Cube: tGDX",
      "topics": [
        "cubeTGDX"
      ]
    },
    {
      "page": "cubeTwoLocusTA",
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